Anafranil, which is clomipramine - is a tricyclic antidepressant. Clomipramine has antiserotonin effect, it eliminates night enuresis, causes loss of appetite. Sedative action is shown due to linkng with H1-histamine receptors, blocking of alpha-adrenoceptors. Medicine eliminates arrhythmia, slows down ventricular conductivity. The anti-depressive effect is implemented due to increase in concentration of noradrenaline, serotonin in synapses because of weakening of the process of recapture of these substances by presynaptic neurons.
Anafranil
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| 75mg × 180 Pills | $1.87 | $336.46 + Bonus - 11 Pills Free Trackable Delivery | $144.00 | Add to cart |
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| 60mg × 60 Pills | $0.93 | $55.85 + Bonus - 4 Pills | - | Add to cart |
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| 25mg × 90 Pills | $0.85 | $76.94 + Bonus - 7 Pills | $27.90 | Add to cart |
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| 10mg × 60 Pills | $0.54 | $32.48 + Bonus - 4 Pills | - | Add to cart |
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Anafranil product description
Drug uses
Anafranil is a tricyclic antidepressant, serotonin and noradrenaline reuptake inhibitor. The drug exerts an antidepressant effect and has antiserotoninergic, antihistaminic and anticholinergic activity. Anafranil is recommended for use in adults and adolescents aged 10 years and older for the treatment of:
- major depression
- cataplexy associated with narcolepsy
- obsessions and compulsions in patients with obsessive-compulsive disorder
The initial recommended dose for adults is 25 mg of Anafranil per day. Then, the daily dose of the antidepressant Anafranil can be gradually increased to about 100 mg per day. Anafranil daily dose can be increased to 250 mg for the treatment of severe psychiatric disorders.
The recommended Anafranil dose for teenagers aged 10 to 17 years (inclusive) is 25 mg a day. Having regard to the tolerance, Anafranil dose for children can be gradually increased up to 100 mg per day. The initial dose of Anafranil for elderly patients is 20-30 mg per day.
Missed dose
The patients are required to adhere to the established dosing regimen and not double an Anafranil dose, even if they missed a dose, during the entire period of mental disorders drug therapy.
To prevent an overdose, the patient should skip the missed dose, if the time for taking the next Anafranil dose is soon to come. If the patient can not remember, whether he or she took Anafranil, it is recommended to skip the next dose, and to take the following antidepressant dose at the usual time.
More information
Anafranil is recommended to be taken in divided doses during meals for reducing the risk of gastrointestinal side effects. After titration, the daily Anafranil dose can be taken once a day, at bedtime. The evening dose of Anafranil helps maintaining a significant antidepressant effect, and causes no unwanted daytime sleepiness.
Storage
Anafranil capsules should be protected from heat and stored in a dry place at temperature below 30°C, out of reach of children.
Anafranil safety information
Warnings
Anafranil should be prescribed with great caution to patients with arrhythmias, cardiovascular insufficiency, conduction disorders. The listed groups of patients should systematically undergo cardiac function monitoring and the ECG. Anafranil may cause chronic constipation in bedridden and elderly patients.
Since the drug has anticholinergic effects, it should be used with caution in patients with narrow-angle glaucoma and increased intraocular pressure. Anafranil may cause symptoms of manic and hypomanic states in patients with major depressive disorder. The dose of Anafranil antidepressant should be reduced, if such symptoms manifest.
Disclaimer
All available information about the tricyclic antidepressant Anafranil is accurate at the time of its publication and should not be considered as a substitute for consulting a psychologist or a psychotherapist. The online pharmacy assumes no responsibility for how and for what purpose people use the published information on antidepressant Anafranil.
Anafranil side effects
Anafranil apsules may cause one or more adverse events. Some undesirable effects of Anafranil may require drug therapy cessation. Clinical studies have shown that about 5% of patients stopped taking Anafranil capsules due to excessive sleepiness.
Unwanted sleepiness is the most common reason for Anafranil abolition. A little more than 1% of the patients, participating in clinical trials, stopped taking Anafranil due to gastrointestinal disorders (constipation, dry mouth, dyspepsia, nausea).
In addition to drowsiness and digestive disorders, Anafranil may cause: vertigo, erectile dysfunction, headache, flushes, sweating, decreased blood pressure, increased appetite, weight increase, anorexia, decreased libido, labored urination, seizures, nervousness, restlessness, tachycardia, tremor, and blurred vision. In most patients with depression, Anafranil causes soft, reversible adverse events, which do not require the antidepressant cessation.
Glucophage - guanyl guanidine, hypoglycemic medicine for peroral takein. At patients with a diabetes mellitus reduces concentration of glucose in blood by oppression of gluconeogenesis in a liver, reduction of absorption of glucose from GIT and increase of its utilization in tissues. Stabilizes or reduces a body weight.
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The medicine belongs to the group of cardiac glycosides. The preparation obtained from the medicinal plants' Woolly Foxglove. It has the following actions: inotropic, vasodilator and moderate diuretic. The pills increase the concussive and systolic volume of the heart, increases the refractory period, reduces atrioventricular conduction, reduces the frequency of contractions of the heart muscle. In the case of stagnation in cardiovascular insufficiency, it has a pronounced vasodilating effect. Lanoxin has a mild diuretic effect, reduces the severity of edema. Overdosage may trigger an increase in the excitability of the myocardium, resulting in disturbances of heart rhythm.
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Levitra - the main component - the active agent Vardenafil which promotes strengthening of blood circulation in generative organs of men. It allows to reach a high level erection at sexual stimulation, and also to increase sensitivity of head of a penis and to make sexual intercourse longer and more pleasant. The main feature of a drug Levitra - quickness of effect, duration of impact on an organism up to 12 hours and a very small number of side effects.
Detrol is taken in case of bladder hyperactivity, shown by frequent imperative desires to urination or urine incontience. Reduces contractile function of bladder and reduces salivation. Causes incomplete bladder emptying, increases quantity of a residual urine and reduces detruzor pressure.
Colospa - myotropic spasmolytic with selective effect on unstriated muscles of digestive tract. Eliminates a spasm, without influencing a normal peristaltics of intestines. Unlike cholinolytic medicine, Colospa does not affect at muscarinic receptor and does not cause characteristic of antispasmodics with muscarinic receptor action of side effects (feeling of dryness in a mouth, vision disorders, an urination delay) that allows for patients to take it at prostatauxe or glaucoma. Taking of Colospa is not followed by development of reflex hypotonia of intestines.
Arcoxia - analgesic and anti-inflammatory drug of a group of highly selective cyclooxygenase-2 inhibitors. The drug has anti-inflammatory, analgesic and antipyretic effect.
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