
Cefaclor is a medicine used to treat the symptoms of various bacterial infections such as Bronchitis, Pharyngitis and Tonsillitis, Urinary Tract Infection, Ear Infections (Otitis Media) and Lower Respiratory Tract Infections. Cefaclor may be used alone or with other medications.
Cefaclor
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Cefaclor belongs to a class of drugs called Cephalosporins, 2nd Generation.
It is not known if Cefaclor is safe and effective in children younger than 1 month of age.
Drug uses
Cefaclor is indicated in the treatment of the following infections when caused by susceptible strains of the designated microorganisms:
Otitis media caused by Streptococcus pneumoniae, Haemophilus influenzae, staphylococci, and Streptococcus pyogenes
Note: β-lactamase-negative, ampicillin-resistant (BLNAR) strains of Haemophilus influenzae should be considered resistant to cefaclor despite apparent in vitro susceptibility of some BLNAR strains.
Lower respiratory tract infections, including pneumonia, caused by Streptococcus pneumoniae, Haemophilus influenzae, and Streptococcus pyogenes
Note: β-lactamase-negative, ampicillin-resistant (BLNAR) strains of Haemophilus influenzae should be considered resistant to cefaclor despite apparent in vitro susceptibility of some BLNAR strains.
Pharyngitis and Tonsillitis, caused by Streptococcus pyogenes
Note: Penicillin is the usual drug of choice in the treatment and prevention of streptococcal infections, including the prophylaxis of rheumatic fever. Cefaclor is generally effective in the eradication of streptococci from the nasopharynx; however, substantial data establishing the efficacy of cefaclor in the subsequent prevention of rheumatic fever are not available at present.
Urinary tract infections, including pyelonephritis and cystitis, caused by Escherichia coli, Proteus mirabilis, Klebsiella spp., and coagulase-negative staphylococci
Skin and skin structure infections caused by Staphylococcus aureus and Streptococcus pyogenes
Appropriate culture and susceptibility studies should be performed to determine susceptibility of the causative organism to cefaclor.
To reduce the development of drug-resistant bacteria and maintain the effectiveness of Cefaclor for Oral Suspension and other antibacterial drugs, Cefaclor for Oral Suspension should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria. When culture and susceptibility information are available, they should be considered in selecting or modifying antibacterial therapy. In the absence of such data, local epidemiology and susceptibility patterns may contribute to the empiric selection of therapy.
Overdosage
Signs and Symptoms
The toxic symptoms following an overdose of cefaclor may include nausea, vomiting, epigastric distress, and diarrhea. The severity of the epigastric distress and the diarrhea are dose-related. If other symptoms are present, it is probable that they are secondary to an underlying disease state, an allergic reaction, or the effects of other intoxication.
Treatment
To obtain up-to-date information about the treatment of overdose, a good resource is your certified Regional Poison Control Center. Telephone numbers of certified poison control centers are listed in the Physicians' Desk Reference (PDR). In managing overdosage, consider the possibility of multiple drug overdoses, interaction among drugs, and unusual drug kinetics in your patient.
Unless 5 times the normal dose of cefaclor has been ingested, gastrointestinal decontamination will not be necessary.
Protect the patient's airway and support ventilation and perfusion. Meticulously monitor and maintain, within acceptable limits, the patient's vital signs, blood gases, serum electrolytes, etc. Absorption of drugs from the gastrointestinal tract may be decreased by giving activated charcoal, which, in many cases, is more effective than emesis or lavage; consider charcoal instead of or in addition to gastric emptying. Repeated doses of charcoal over time may hasten elimination of some drugs that have been absorbed. Safeguard the patient's airway when employing gastric emptying or charcoal.
Forced diuresis, peritoneal dialysis, hemodialysis, or charcoal hemoperfusion have not been established as beneficial for an overdose of cefaclor.
Storage
Store the capsules and tablets at room temperature and away from excess heat and moisture (not in the bathroom). The tablets should also be stored away from light. Keep liquid medicine in the refrigerator, tightly closed, and dispose of any unused medication after 14 days.
Safety information
Warnings
BEFORE THERAPY WITH CEFACLOR IS INSTITUTED, CAREFUL INQUIRY SHOULD BE MADE TO DETERMINE WHETHER THE PATIENT HAS HAD PREVIOUS HYPERSENSITIVITY REACTIONS TO CEFACLOR, CEPHALOSPORINS, PENICILLINS, OR OTHER DRUGS. IF THIS PRODUCT IS TO BE GIVEN TO PENICILLIN-SENSITIVE PATIENTS, CAUTION SHOULD BE EXERCISED BECAUSE CROSS-HYPERSENSITIVITY AMONG β-LACTAM ANTIBIOTICS HAS BEEN CLEARLY DOCUMENTED AND MAY OCCUR IN UP TO 10% OF PATIENTS WITH A HISTORY OF PENICILLIN ALLERGY.
IF AN ALLERGIC REACTION TO CEFACLOR OCCURS, DISCONTINUE THE DRUG. SERIOUS ACUTE HYPER-SENSITIVITY REACTIONS MAY REQUIRE TREATMENT WITH EPINEPHRINE AND OTHER EMERGENCY MEASURES, INCLUDING OXYGEN, INTRAVENOUS FLUIDS, INTRAVENOUS ANTIHISTAMINES, CORTICOSTEROIDS, PRESSOR AMINES, AND AIRWAY MANAGEMENT, AS CLINICALLY INDICATED.
Antibiotics, including cefaclor, should be administered cautiously to any patient who has demonstrated some form of allergy, particularly to drugs.
Clostridium difficile associated diarrhea (CDAD) has been reported with use of nearly all antibacterial agents, including Cefaclor for Oral Suspension, USP, and may range in severity from mild diarrhea to fatal colitis. Treatment with antibacterial agents alters the normal flora of the colon leading to overgrowth of C. difficile.
C. difficile produces toxins A and B which contribute to the development of CDAD. Hypertoxin-producing strains of C. difficile cause increased morbidity and mortality, as these infections can be refractory to antimicrobial therapy and may require colectomy. CDAD must be considered in all patients who present with diarrhea following antibiotic use. Careful medical history is necessary since CDAD has been reported to occur over two months after the administration of antibacterial agents.
If CDAD is suspected or confirmed, ongoing antibiotic use not directed against C. difficile may need to be discontinued. Appropriate fluid and electrolyte management, protein supplementation, antibiotic treatment of C. difficile, and surgical evaluation should be instituted as clinically indicated.
Disclaimer
The information on this page is not intended to be a substitute for professional medical advice. Do not use this information to diagnose or treat your problem without consulting your doctor.
Side effects
Cefaclor may cause serious side effects including:
- stomach upset,
- headache,
- nausea,
- vomiting,
- diarrhea,
- stomach pain,
- persistent nausea or vomiting,
- yellowing of the skin or eyes (jaundice),
- dark urine,
- new signs of infection (sore throat, fever),
- easy bruising or bleeding,
- change in the amount of urine,
- mood changes,
- confusion,
- severe intestinal condition (Clostridium difficile-associated diarrhea),
- blood or mucus in your stool,
- white patches in your mouth,
- change in vaginal discharge,
- rash,
- itching,
- swelling of the face, tongue or throat,
- unusual joint pain, and
- trouble breathing
Get medical help right away, if you have any of the symptoms listed above.
The most common side effects of Cefaclor include:
- diarrhea,
- stomach upset,
- headache,
- nausea,
- vomiting,
- vaginal itching or discharge, and
- hypersensitivity reactions
Tell the doctor if you have any side effect that bothers you or that does not go away.
These are not all the possible side effects of Cefaclor. For more information, ask your doctor or pharmacist.
Allopurinol - a drug that promotes the excretion of uric acid and the removal of urinary calculi.

Brand Viagra - a drug from Pfizer, with a basic chemical called Sildenafil Citrate, is a first developed pharmaceutical to cure the difficulties with erection. It functions approximately within 4-5 hours, must be taken an hour prior to sex.

Cialis Professional - effective tablets for improvement of erection. They begin to work in 15 minutes from the moment of taking and actions for 36 hours. They can cause not less than 10, but no more than 16 erections. The medicine increases duration of sexual intercourse. The tablets are successfully used for reduction of time for recovery of erection after ejaculation.

A semi-synthetic antibiotic from the macrolides group for oral administration. The list of indications includes: infections of the upper and lower respiratory tract (pharyngitis, bronchitis, pneumonia, bacterial infection in COPD, panbronchiolitis, bronchiectasis), respiratory tract (tonsillitis, sinusitis, otitis media), skin and soft tissues (erysipelas, phlegmon, furuncles, folliculitis, impetigo, pyoderma), urinary tract (urethritis, endometritis, cervicitis, vaginitis, including sexually transmitted infections, except gonorrhea), oral cavity (periodontitis), bones (periostitis, chronic osteomyelitis); scarlet fever, diphtheria, whooping cough, trachoma, migratory erythematous rash, brucellosis.

Epivir-HBV selectively suppresses replication of HIV-1 and HIV-2 in vitro. Gets into the cells induced by a virus passes into an active form - lamivudine 5 triphosphate which is the weak inhibitor of RNA and DNA-dependent return transcriptase of HIV.

Frumil - combined diuretic medicine which consists of AMILORIDE HYDROCHLORIDE ANHYDROUS and FRUSEMIDE which action is caused by its components; it has diuretic and hypotensive effect. Amiloride reduces egestion of K+ and Mg2+. FRUSEMIDE "looping" diuretic. The combination of components of a drug reduces a risk of development of hypopotassemia and hypomagnesiemia.

Advair Diskus is a drug manufactured to cope with diseases which attack bronchi and lungs. Medics prescribe it for people with COPD, pant, wheeze, dyspnea, pulmonary emphysema, and chronic bronchitis. It consists of two main components: a corticosteroid (Fluticasone) and a long-acting beta agonist (Salmeterol). The first component reduces the irritation and the swelling of lungs and bronchi. The second component makes the breathing easier. Doctors prescribe the drug for patients who need a combination treatment when one medication doesn’t work. The medicine is a part of a long-term medication as it isn’t effective in case of sudden asthma attacks.

Sinequan - antidepressant, which is taken as prescribed by the doctor in case of the following indications: depression, anxiety and sleep disturbance in neuroses, alcoholism, organic diseases of the central nervous system, psychoneurotic disorders with anxiety, depression, psychotic depression (including the involutionary, reactive depressive phase of manic-depressive Psychosis). In general therapeutic practice - duodenal ulcer, dumping syndrome, premenstrual syndrome, chronic pain in cancer patients, skin itching, chronic idiopathic urticaria.

is given to patients for treating severe acne that do not respond to other medicines

Desyrel antidepressive medicine, a derivative of thiazolopyridine; renders thymoleptic, anxiolytic, sedative and myorelaxation action. It is prescribed for treatment of various forms of depression (endogenous, psychotic, neurotic, somatogenic) including with the expressed state anxiety.

Atarax - renders spasmolytic, sympatholytic and soft analgesic effect. Under the effect of the drug it is increased the general duration of a dream, reduction of quantity and duration of night awakenings, decreases the muscle tone, it does not cause memory disturbance. It isn't reffered to CNS depressants, but can oppress the activity of separate zones of subcrustal area. It possesses antihistaminic and bronchodilating effect. In usual therapeutic dose the drug has no effect on secretory and acid-forming. It is effective in treatment of itch at various allergic dermatitis, urticaria and eczema.

Januvia - is a drug for adult patients with type 2 diabetes mellitus, in order to control the glycemic level under conditions of monotherapy as part of combined treatment regimens. The drug is prescribed to patients with ineffectiveness of diet therapy in combination with optimal physical activity, with the impossible use of metformin because of its intolerance.

Actos, which is pioglitazone - is prescribed to patients with diabetes of type 2 (both as monotherapy, and in a form of the combined therapy with sulphonylurea, metformin or insulin as additional medicine to dietotherapy and physical exercises). Pioglitazone represents peroral hypoglycemic medicine of Thiazolidinediones alignment which effect depends on insulin presence. It is a high-selective agonist of gamma receptors, activated by proliferator of peroxysom (PPAR-γ).

Grifulvin V - the antifungal antibiotic, which is taken at mycoses of skin, hair and nails, and effective concerning fungus of the sort Trichophyton, Microsporum, Epydermophyton, Achorionum; causes disturbance of structure of mitotic spindle and synthesis of a cell wall in chitin fungus, suppresses division of fungal cells in metaphase and synthesis of protein because of disruption of linking with template-RNA.

An antituberculosis drug which acts bacteriostatically; it enters the actively growing cells of mycobacteria by inhibiting RNA synthesis, interferes with cellular metabolism, causing cessation of reproduction and death of bacteria. Active only in relation to the intensively dividing cells. Inhibits the growth and reproduction of tuberculosis mycobacterium resistant to streptomycin, isoniazid, PASK, ethionamide, kanamycin. In the conditions of monotherapy, the resistance of mycobacteria develops fast enough.

Erythromycin is a macrolide antibiotic of bacteriostatic action. In high concentrations and relatively high-sensitivity microorganisms may have a bactericidal effect.

Sumycin - An antibiotic based on tetracycline, a brand of such pharmaceutical companies as Bristol-Myers Squibb, Apothecon, Par Pharmaceutical.

Lisinopril is an antihypertensive, vasodilating, cardioprotective drug, an ACE inhibitor that is used to treat hypertension, heart failure, acute myocardial infarction, diabetic nephropathy.

Zestoretic - tablets containing 12,5Mg of Hydrochlorothiazide and 10Mg of Lisinopril, as active ingredients. It is hypotensive, vasodilating, natriuretic, cardioprotective medical preparation.The drug is used to treat arterial hypertension, also in order to reduce the risk of cardiovascular disease and mortality in patients with hypertension and left ventricular hypertrophy, manifesting cumulative reduction in the incidence of cardiovascular death, incidence of stroke and myocardial infarction.

Viagra Soft Flavored - chewing tablet viagra, which has a mint taste and differs from usual viagra by mode of administration and speed of effect. Unlike usual viagra - Viagra Soft Flavored should be resolved or chewed. So at administration of drug it is possible to take alcohol and greasy food that is not recommended at taking of any other type of viagra. The effect of Viagra Soft Flavored comes in 30 minutes after reception, and lasts for 4 hours.

Aurogra is the erectile dysfunction drug that belongs to Viagra analogs. The drug is also taken in case of premature ejaculation and enlarged prostate. The drug is prescribed when erectile dysfunction occurs naturally (due to aging) and if it’s the result of bad habits (smoking, alcohol abuse, drug dependence) and diseases. Its main component is Sildenafil Citrate. It’s created to stimulate the natural process of erection in men. Blue diamond pills make the blood flow to the pelvic area and cause a stable erection. The effect of each pill is strong and lasts up to 5 hours.

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Levitra - the main component - the active agent Vardenafil which promotes strengthening of blood circulation in generative organs of men. It allows to reach a high level erection at sexual stimulation, and also to increase sensitivity of head of a penis and to make sexual intercourse longer and more pleasant. The main feature of a drug Levitra - quickness of effect, duration of impact on an organism up to 12 hours and a very small number of side effects.

Apcalis SX - Tadalafil pills, released by Ajanta in 20mg dosage. Being equal to Cialis by an outcome and the way of an action, this innovative medical mean is also directed at enhancing the hardness of the male sexual organ and reducing the period on the restoration of the male potency after the sexual act.

Albenza - anthelmintic agent which is active concerning adult individuals and larval forms. Albendazole influences polymerization of β-tubulin, which stops it. As a result, occurs violation of formation of microtubules in intestines of helminths, the ability of vermis to acquire glucose is suppressed. It is blocked the normal intracellular migration of organellas, and it is prevented the synthesis of ATP in their muscular tissue. Creation of therapeutic concentration of albendaloze leads to death of helminths. Medicine causes death of nematodes (Necator americanus, Strongyloides stercoralis, Enterobius vermicularis, Trichuris trichiura, Ascaris lumbricoides, Cutaneous Larva Migrans, Ancylostoma duodenale), cestode (pig, bull and dwarf tapeworm), trematode (Clonorchis sinensis, Opisthorchis viverrini), elementary (Lamblia).

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Levaquin is used to treat infections of the lower respiratory tract, urinary tract, kidneys, skin, soft tissues, chronic bronchitis, acute sinusitis, chronic bacterial prostatitis and tuberculosis. The drug is a fluoroquinolone, a broad-spectrum antimicrobial bactericide. It blocks DNA gyrase and topoisomerase IV, disrupts supercoiling and cross-linking of DNA gaps, suppresses DNA synthesis, causes profound morphological changes in the cytoplasm, cell wall and bacterial membranes.

Trecator SC - an anti-TB drug (antituberculous), contains Ethionamide as a basic substance, the drug is prescribed for the treatment of multidrug-resistant type of tuberculosis, with the mycobacterium tuberculosis susceptible to it.

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Antiepileptic agent. The use of Lamictal reduces the pathological activity of neurons without inhibiting their function. Stabilizes the neuronal membranes by affecting Na + channels, blocks excessive release of excitatory amino acids (mainly glutamate), without reducing its normal release.

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Naltrexone - complex treatment of alcohol dependence. It is also attributed to the prevention of the pharmacological effects of exogenous opioids and the maintenance of a non-opioid state in patients with opioid dependence.

Flexeril - medicine acting against muscular spasms. It possesses sedative action, it is not recommended to be engaged in potentially dangerous types of activity if a person takes Flexeril. As well as in a case with narcotic analgetics, Flexeril is not recommended to take longer than seven days as in case of a long taking there can be a dependence.

Rogaine is the brand recommended by trichologists all over the world for hair restoration. For more than 20 years, the medicine has shown excellent results, which are confirmed in more than 2000 clinical trials. Using Rogaine 5 one is able to grow new hair and stop further hair loss. The lotion has no smell and is easy to use. The medicine is a great discovery that stops baldness and regains self-confidence. Rogaine lotion Extra Strength 5% Minoxidil stimulates the growth of new healthy hair. The first signs of growth appear after 2-3 months of regular use of the drug.

Propecia - an anti-hormonal drug. Used to reduce the size of the prostate gland, to increase the maximum speed of urine outflow, reducing the risk of developing acute urinary retention. The drug also turned out to be effective in the treatment of men’s alopecia.

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Diabecon is aimed at increasing peripheral glucose intake, restoring B cells, increasing C – peptide levels. Diabecon has antioxidant properties, protecting cells from oxidative stress. The drug eliminates the painful symptoms of diabetes: polyuria, fever, burning feet and hands. Symptoms are eliminated not immediately after administration but within two to three weeks. This is due to changes in chemical processes in the body that cause symptoms of the disease. Diabecon naturally reduces craving for sweets, restores the patient's appetite, normalizes the functions of liver and kidney.

The medicine has many natural ingredients with astringent and antimicrobial effects. It removes microorganisms which are in charge of continuous and acute diarrhea. Diarex insures the strengths of the intestinal tract. Being antioxidative, it improves health for the digestive and gastrointestinal tract. Anti-inflammatory and calmative functions of the pill make healing of the intestinal mucosa faster, reduce muscle spasm and abdominal colic connected with the intestinal infection.

Speman enhances male sexual performance by means of substances of vegetable origin. Extracts of seeds, stems, leaves and roots coming from nine medicinal plants are selected for their spermatogenesis-boosting properties. The drug facilitates and stimulates the process of sperm generation, increasing the mobility of spermatozoids and reducing the thickness of semen (which, consequently, improves fertilizing capabilities of sperm). Spenman decongests the prostate gland and returns its size back to unenlarged, in turn restoring both the normal urinary function and the male’s libido.

Doxazosin is used for treating hypertension (high blood pressure) and enlarged prostate. The drug increases the blood flow by expanding the veins and arteries. It also relaxes the muscles of the prostate and the neck of urinary bladder, making it easier to urinate.

Haldol antipsychotic remedy, butyrophenone derivative. It has a powerful antipsychotic effect, moderate sedation. The mechanism of antipsychotic action of haloperidol is associated with the blockade of dopamine receptors in the mesocortex and limbic system.

Tegretol - anticonvulsant drug, dibenzodiazepine derivative. It also has neurotropic and psychotropic action. Indications for use: epilepsy, alcohol withdrawal syndrome, idiopathic trigeminal neuralgia and trigeminal neuralgia with multiple sclerosis (typical and atypical), idiopathic neuralgia of the glossopharyngeal nerve, diabetic neuropathy with pain syndrome, diabetes insipidus of central genesis,

Urispas is an oral antispasmodic drug approved to prevent bladder spasms caused by urethral catheterization, infectious and /or inflammatory diseases of the urogenital system or neurological disorders.

Colospa - myotropic spasmolytic with selective effect on unstriated muscles of digestive tract. Eliminates a spasm, without influencing a normal peristaltics of intestines. Unlike cholinolytic medicine, Colospa does not affect at muscarinic receptor and does not cause characteristic of antispasmodics with muscarinic receptor action of side effects (feeling of dryness in a mouth, vision disorders, an urination delay) that allows for patients to take it at prostatauxe or glaucoma. Taking of Colospa is not followed by development of reflex hypotonia of intestines.

Thiol derivative, a competitive hypoxanthine antagonist, has an immunosuppressive and cytostatic effect. It is used for prevention of rejection reaction in kidney transplantation, treatment of rheumatoid arthritis, chronic active hepatitis, SLE, dermatomyositis, periarteritis nodosa, acquired hemolytic anemia, gangrenous pyoderma, psoriasis, Crohn's disease, ulcerative colitis and myopathy.

Zanaflex (tizanidine) - the drug with an antispastic effect in increased muscle tone, relieves spasms and clonic convulsions.
Assign with painful muscular spasms associated with static and functional spine lesions (cervical and lumbar syndrome), and after surgery for a herniated disc or osteoarthritis of the thigh, as well as for spasms and pain due to multiple sclerosis, chronic myelopathy, degenerative diseases of the spinal cord brain, stroke, with cramps of central origin.

Xeloda is a cytostatic drug. The drug is used for the treatment of patients with metastatic or locally advanced breast cancer, including after an ineffective chemotherapy course, which included anthracycline drugs and taxanes, and also if the patient has contraindications to anthracyclines.

An anti-climax combined drug which has estrogenic and gestagenic effect, restores the balance of endogenous hormones.
Estrogens regulate the development of the female reproductive system functions’ preservation, the formation of female secondary sex characteristics. The list of indications includes: vasomotor symptoms associated with estrogen deficiency in the body, osteoporosis associated with estrogen deficiency, atrophic urethritis and atrophic vaginitis.

Exelon drug for treatment of Alzheimer's disease with poorly and moderately expressed dementia. By the principle of action of Exelon it is the Selection inhibitor of acetylcholinesterase of a brain.

Tadalafil is phosphodiesterase type 5 inhibitor and has similar actions to the other phosphodiesterase type 5 inhibitors such as Sildenafil Citrate.

Besivance is a medicine used to treat the symptoms of Bacterial Conjunctivitis.
Besivance may be used alone or with other medications.
Besivance belongs to a class of drugs called Quinolones, Ophthalmic.
It is not known if Besivance is safe and effective in children younger than 1 year of age.

Bimat is used for Glaucoma, Ocular hypertension, Lengthening eyelashes and other conditions.

Paroxetine is used to treat depression, panic attacks, obsessive-compulsive disorder (OCD), anxiety disorders, and post-traumatic stress disorder.

is given to patients for treating severe acne that do not respond to other medicines
