Differin is a white gel or cream. The drug is used to treat acne. It can also be used to combat comedones. Differin monotherapy is helpful in case of minor acne. For the treatment of severe and moderate degree of acne, the drug is used in conjunction with systemic drugs (antiandrogens, antibacterial agents). The drug is well tolerated. It rarely causes irritation, so its use is good even for those who have sensitive skin with acne. The gel is more suitable for oily skin and the cream suits better for dry skin.
Differin
| Package | tube | Total price | Save | Order |
|---|---|---|---|---|
| 15gr × 5 Tubes | $25.76 | $128.82 | - | Add to cart |
| 15gr × 10 Tubes | $18.52 | $185.18 + Bonus - 4 Pills | $72.40 | Add to cart |
| 15gr × 15 Tubes | $16.10 | $241.54 + Bonus - 4 Pills Free Trackable Delivery | $144.90 | Add to cart |
| 15gr × 25 Tubes | $14.17 | $354.25 + Bonus - 4 Pills Free Trackable Delivery | $289.75 | Add to cart |
| Package | tube | Total price | Save | Order |
|---|---|---|---|---|
| 15gm × 20 Tubes | $14.89 | $297.89 + Bonus - 4 Pills Free Trackable Delivery | - | Add to cart |
Your order will be packed safely and securely and dispatched within 24 hours. This is exactly how your parcel will look like (pictures of a real shipping item). It has the size and the look of a regular private letter (9.4x4.3x0.3 inches or 24x11x0.7cm), and it does not disclose its contents
Product description
Differin belongs to the category of topical retinoids aimed at the treatment of acne vulgaris that occurs in young people starting from 12 years of age. The name Acne vulgaris indicates the condition of the face, back or chest characterized by the presence of blackheads, whiteheads, and pimples. Surveys show that at least 85% of the US entire population is affected by acne at a certain point in their life.
The active substance of Differin is Adapalene that works due to its properties of a vitamin A derivative. It binds to nuclear receptors that are specific for retinoic acids. At the same time, it avoids binding to the cytosolic receptor protein. This selectivity allows adapalene to modulate the processes of keratinization, inflammation development, and cellular differentiation.
The Nonprescription Drugs Advisory Committee by FDA has confirmed that the pharmacological safety profile and the application data amassed for adapalene gel 0.01% are sufficient to make the product available over-the-counter.
Directions for use
Differin Gel 1mg/g should be applied as follows:
- Clean the acne-affected skin using a mild lotion or a soap.
- Rinse carefully and dry with easy movements.
- Spread Differin gel thinly to the affected areas. Apply it to both the pimples and surrounding skin. Leave the gel for a minute to dry.
- Do not remove or wash the gel from your face after application. Avoid touching or rubbing the treated areas.
Try not to use oil-based cosmetics and ointments. Makeup products providing a drying, abrasive, or peeling effect may lead to additional irritation of the skin.
Safety information
Patients should bring sunlight exposure to the minimum, including solarium lamps and sunlamps, during the treatment with Differin. If it is not possible to avoid the exposure, use sunscreens and protective clothing. Extreme wind or cold temperatures may also cause irritation.
Differing should not come in contact with the lips, wings of the nose, eyes, and mucous membranes. Avoid applying the medicine on cuts, scratches, patches of skin damaged by eczema or sunburns. Similarly to all retinoids, adapalene is not compatible with skin waxing.
Caution should be observed when combining Differin with other topical-action products, such as medicated soaps or cleansers with abrasive effect, as well as alcohol-containing products or astringents. Use with extra care any preparation comprising resorcinol, sulfur, or salicylic acid when staying with Differin.
This medicine has an unknown potential for use in pregnant women or those planning pregnancy. The data by FDA shows that about 12% of adult American women suffer from moderate to severe acne. The study comparing the safety risk against the pharmaceutical’s beneficial potential in animals has confirmed adapalene to be teratogenic and malformation-inducing when given orally at high dose levels (25 mg/kg and 60 mg/kg).
Side effects
In placebo-controlled clinical studies, use of Differin was most commonly associated (≥1%) with skin dryness, irritation and discomfort, itchy feelings, skin desquamation, and painful sunburns.
The above are mild reactions and they normally pass quickly. However, you should not postpone your visit to the doctor if you notice or are bothered by any of the following adverse effects: contact dermatitis/eczema-like manifestations, acne flare, facial swelling, acute conjunctivitis.
Abilify is designed for patients with diagnosis named schizophrenia. It is used either during the exacerbation period or for maintenance treatment. Abilify is also prescribed in cases of an acute manic episodes of type 1 in manic-depressive psychosis, and as a supportive treatment for bipolar affective disorders. Abilify can be used as an additional treatment during depressive disorders. According to some experts, the drug can be used in order to treat alcoholism.
Viagra Professional - Advantage of Professional Viagra from usual Viagra is that it works twice longer (6 - 8 hours) and has a stronger effect. Strengthens desire, improves brightness of sexual feelings and increases duration of sexual intercourse.
Viagra Oral Jelly - a new formula of the drug Viagra. Sildenafil - 100 mg. It is prescribed for men with a weak potentiality. Helps to recover libido and to improve sexual activity. Accelerates process of excitement of reproductive system. It makes erection brighter. Considerably increases duration of sexual intercourse. Besides, drug has various pleasant tastes, it is convenient to carry in a pocket or in a purse. Hurry to try it!
Floxin - antimicrobic broad-spectrum agent from group of fluroquinolone. It is active concerning the microorganisms producing beta lactamelements and fast-growing atypical mycobacteria. It is taken at respiratory infection, the ENT organs, skin, soft tissues, bones, joints, abdominal cavity, urinary tract.
Avalide is an effective medicine which aim is to lower the blood pressure. Hypertension provokes serious diseases as strokes, heart attack, and problems with the kidney. An angiotensin receptor blocker and diuretic are the basic components of the drug. The first one relaxes the walls of the blood vessels letting the blood move freely without the pressure. The second component stimulates urination so that a patient can get rid of extra salt and water which also provoke high blood pressure.
Caverta - another affordable version of Indian Viagra created by Ranbaxy, released as Caverta 100mg and Caverta 50mg.
The drug dilates coronary vessels (mostly arterioles) and causes a significant increase in volumetric blood flow velocity. Increases the content of oxygen in venous blood of coronary sinus and its absorption by myocardium. Promotes the development of collateral coronary circulation, reduction in a systemic vascular resistance, improves microcirculation, has angioprotective action.
Zerit - treatment of infection caused by HIV, with severe clinical manifestations and ineffectiveness or intolerance of zidovudine, and other antiretroviral drugs. The nucleoside analogue of thymidine is phosphorylated by cellular enzymes to its active form - stavudine triphosphate. Suppresses reverse transcriptase of HIV, cellular DNA polymerases (beta and gamma), inhibits the synthesis of viral and mitochondrial DNA. It is active against HIV-1.
An antiparkinsonian agent. A non-ergoline selective agonist of dopamine D2 and D3 receptors. A possible mechanism of action in the treatment of Parkinson's disease , associated with a stimulating effect on the postsynaptic D2 receptors of the basal nuclei in the brain.
Actonel, which is risedronate - is prescribed for treatment and prevention of osteoporosis (post-menopausal, caused by corticosteroids), Paget disease. Risedronate binds to substance of a bone tissue, inhibits its resorption mediated by osteoclasts and reduces a bone turn (does not break process of formation of a bone). It increases the biomechanical strength and volume of bone mass. The maximum decrease in a bone turn is observed in 3-6 months, remaining at the same level during a course of treatment.
is given to patients for treating severe acne that do not respond to other medicines
Speman enhances male sexual performance by means of substances of vegetable origin. Extracts of seeds, stems, leaves and roots coming from nine medicinal plants are selected for their spermatogenesis-boosting properties. The drug facilitates and stimulates the process of sperm generation, increasing the mobility of spermatozoids and reducing the thickness of semen (which, consequently, improves fertilizing capabilities of sperm). Spenman decongests the prostate gland and returns its size back to unenlarged, in turn restoring both the normal urinary function and the male’s libido.
Synthroid finds use as a hormone-regulating agent for managing low levels of triiodothyronine/thyroxine. It also has a pronounced therapeutic effect on goiters of certain types. Synthroid often accompanies surgeries and other medical means of treating thyroid cancer. The drug compensates for the insufficient production of thyroid hormones by standing in their place as a synthetic substitution. Compensations of this kind help the patient’s body to restitute the normal rate of metabolism. Synthroid also helps to fight obesity due to its ability to remove the initial thyroid gland-related causes as such.
Dapsone antibacterial agent, which is active concerning Mycobacterium leprae and tuberculosis. It has bacteriostatic action similar to antagonists of p-aminobenzoic acid.
The effect of clomipramine is to inhibit the opposite neurological catching of serotonin and noradrenaline. The most crucial is the suppression of serotonin recapture. In addition, the medicine has a broad range of other pharmacological actions: alpha 1-adrenoliticheskoe, anticholinergic, antigestagen and antiserotonergic. The pill acts on the depressive disorder in general. The difference is usually observed after 2-3 weeks of therapy. Acticine also has a specific influence on obsessive-compulsive disorders.
